1. Trinucleotide repeat amplification ,ion channel disease, genetic metabolic disease, abnormal protein product deposition , metal ion transport disorder.

2.Friedreich type ataxia is the most common autosomal recessive disorder. Spinocerebellar ataxia included SCAI-SCA29,SCA9 unknown, SA24 autosomal recessive inheritance and X-linked recessive heredity were rare.

The main genetic mode of peroneal muscular dystrophy is autosomal dominant inheritance.